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Louise Henderson NCI Grant to study Cumulative Risk and Multilevel Impact of False Positive Findings

November 11, 2024

July 2024 Professor Henderson received an estimated $3.2 million award from the National Cancer Institute for her research titled Lung Cancer Screening: Cumulative Risk and Multilevel Impact of False Positive Findings.  Abstract: The National Lung Screening Trial demonstrated the efficacy of lung cancer screening (LCS) with low-dose computed tomography in reducing 5-year lung cancer mortality by 20%, albeit with high rates of false-positive results. The US Preventive Services Task Force recommends annual LCS with LDCT for individuals ages 50- 80 years who currently or formerly (quit within 15 years) smoked with a 20-pack-year history. Despite the task force Grade B recommendation, … Read more


Lund and Henderson awarded new grant to apply causal inference methods to improve estimation of the real-world net benefits of lung cancer screening

May 15, 2024

Drs. Jennifer Lund and Louise Henderson were awarded a new grant to apply causal inference methods to improve estimation of the real-world net benefits of lung cancer screening (LCS). Previous studies have demonstrated that lung cancer screening using LDCT can reduce lung cancer mortality, but this comes with the cost of relatively high rates of false positive results and complications from downstream procedures. However, we also see that behaviors of patients who screen in the “real world” are different from those in randomized clinical trials (RCTs), specifically that only around 10-20% of eligible individuals actually undergo LCS, and of those, … Read more


IASLC 2023 North America Conference on Lung Cancer

April 24, 2024

Dr. Patricia Rivera presented on the topic “Comparison of Baseline Risk of Developing and Dying from Lung Cancer in Screen Eligible General Versus Trial Populations” at the International Association for the Study of Lung Cancer 2023 North America Conference on Lung Cancer in Chicago, IL.


2023 UNC Radiology Research Symposium

April 24, 2024

Lindsay Lane presented “Evaluation of Longitudinal Adherence to Annual Lung Cancer Screening” at the 2023 UNC Radiology Research Symposium. This annual meeting is hosted by the Department of Radiology and attended by researchers, clinicians, and students from across the UNC and surrounding communities. Lindsay Lane and Dr. Danielle Durham also presented posters on Longitudinal Adherence and “Comparison of measure of longitudinal adherence in lung cancer screening.”


Dr. Henderson presents research poster at ICSN 2023

June 30, 2023

Dr. Henderson a research poster on the topic of Evaluation of Longitudinal Adherence to Annual Lung Cancer Screening at the International Cancer Screening Network Meeting in Turin, Italy in June 2023 https://icsn2023.it/  


White Ribbon Project – UNC Early Detection Lung Cancer Program

May 8, 2023

On Tuesday 4/18/23, UNC celebrated UNC primary care physicians and researchers working as part of the UNC Early Detection Lung Cancer Program through a White Ribbon Project event. As part of this, Chris Draft presented white ribbons to the team. https://www.thewhiteribbonproject.org/bios/chris-draft)  


2022 Radiology Research Symposium

November 7, 2022

Dr. Durham and Lindsay Lane shared research posters at the 2022 Radiology Departmental Research Symposium.


Dr. Henderson discusses lung cancer screening guidelines at CHEST 2022 Conference

October 19, 2022

“Some have raised concerns that the 2013 USPSTF lung cancer screening eligibility criteria created racial and ethnic disparities,” Dr. Henderson said. “And while expanded eligibility criteria are an important step to equity, it’s not enough to eliminate disparities. We must address disparities and implementation challenges to get lung cancer screening to areas in need.” Read the Full Article at: Experts share latest updates in lung cancer screening guidelines


NC LSR Research Presented at ATS2022 Conference

May 20, 2022

Drs. Henderson, Rivera, and Metwally presented research at the American Thoracic Society’s 2022 Conference in San Francisco. Attendance at conferences allows us to share our research with an even broader audience and stay current with the exciting developments made in this field. Details about our poster sessions are at https://conference.thoracic.org/program/clinical-scientific-sessions/


Eman Metwally awarded ATS 2022 Scholarship

May 19, 2022

  Eman Metwally, MD-PhD, MPS received the Assembly on Thoracic Oncology 2022 Abstract Scholarship. Dr. Metwally is a CCEP Postdoctoral Fellow who works closely with the NC Lung Screening Registry and related projects. Drs. Henderson, Rivera, and Metwally attended to the Assembly on Thoracic Oncology 2022 Conference to present research findings.